Publication
Title
Antibacterial, antifungal and cytotoxic activities of two flavonoids from **Retama raetam** flowers
Author
Abstract
We have investigated the antibacterial, antifungal and cytotoxic activities of two flavonoids isolated from Retama raetam flowers using the disc diffusion and micro-dilution broth methods. The cytotoxic activity was tested against Hep-2 cells using the MTT assay. The compounds licoflavone C (1) and derrone (2) were active against Pseudomonas aeruginosa and Escherichia coli (7.81-15.62 mu g/mL) and showed important antifungal activity. Strong antifungal activity against Candida species (7.81 mu g/mL) was for example found with compound 2. The tested compounds also showed strong cytotoxicity against Hep-2 cells. These two compounds may be interesting antimicrobial agents to be used against infectious diseases caused by many pathogens.
Language
English
Source (journal)
Molecules: a journal of synthetic chemistry and natural product chemistry. - Bazel
Publication
Bazel : 2012
ISSN
1420-3049
Volume/pages
17:6(2012), p. 7284-7293
ISI
000305800400076
Full text (Publisher's DOI)
Full text (open access)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 03.08.2012
Last edited 16.06.2017
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