Publication
Title
Finding a better drug for epilepsy : antiinflammatory targets
Author
Abstract
This monograph summarizes one of the sessions of the XI Workshop on Neurobiology of Epilepsy (WONOEP), and provides a critical review of the current state of the field. Speakers and discussants focused on several broad topics: (1) the coexistence of inflammatory processes encompassing several distinct signal-transduction pathways with the epileptogenic process; (2) evidence for the contribution of specific inflammatory molecules and processes to the onset and progression of epilepsy, as well as to epilepsy-related morbidities including depression; (3) the complexity and intricate cross-talk of the pathways involved in inflammation, and the discrete, often opposite roles of a given mediator in neurons versus other cell types. These complexities highlight the challenges confronting the field as it aims to define inflammatory molecules as promising targets for epilepsy prevention and treatment.
Language
English
Source (journal)
Epilepsia. - Boston, Mass.
Publication
Boston, Mass. : 2012
ISSN
0013-9580
DOI
10.1111/J.1528-1167.2012.03520.X
Volume/pages
53 :7 (2012) , p. 1113-1118
ISI
000305944600006
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Research group
Project info
Longitudinal in vivo follow-up of PET biomarkers in neurological disease models.
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identifier
Creation 13.09.2012
Last edited 09.10.2023
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