Title
Economic evaluations of childhood influenza vaccination : a critical review Economic evaluations of childhood influenza vaccination : a critical review
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
Auckland ,
Subject
Economics
Pharmacology. Therapy
Human medicine
Source (journal)
Pharmacoeconomics. - Auckland, 1998 - 2015
Volume/pages
30(2012) :8 , p. 647-660
ISSN
1170-7690
ISI
000307033300003
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
The potential benefits of influenza vaccination programmes targeted at children have gained increasing attention in recent years. We conducted a literature search of economic evaluations of influenza vaccination in those aged 18 years. The search revealed 20 relevant articles, which were reviewed. The studies differed widely in terms of the costs and benefits that were included. The conclusions were generally favourable for vaccination, but often applied a wider perspective (i.e. including productivity losses) than the reference case for economic evaluations used in many countries. Several evaluations estimated outcomes from a single-year epidemiological study, which may limit their validity given the year-to-year variation in influenza transmissibility, virulence, vaccine match and prior immunity. Only one study used a dynamic transmission model able to fully incorporate the indirect herd protection to the wider community. The use of dynamic models offers great scope to capture the population-wide implications of seasonal vaccination efforts, particularly those targeted at children.
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