Publication
Title
The genetics of dementia with Lewy bodies : what are we missing?
Author
Abstract
Dementia with Lewy bodies is a complex brain disorder and a key member of the Lewy body disease spectrum. Its genetic etiology is unclear, and information is scattered. However, the results of molecular genetic studies imply a genetic and mechanistic overlap with Alzheimer disease, Parkinson disease with dementia, and Parkinson disease. In this review, we provide a comprehensive overview of the current studies on dementia with Lewy bodies heritability, genetic etiology, and genetic heterogeneity. We conclude with a critical discussion of the missing heritability in dementia with Lewy bodies and encourage scientists to further explore the underlying mechanisms of this disease. Arch Neurol. 2012; 69(9): 1113-1118. Published online May 28, 2012. doi:10.1001/archneurol.2011.3678
Language
English
Source (journal)
Archives of neurology / American Medical Association. - Chicago, Ill., 1960 - 2012
Publication
Chicago, Ill. : 2012
ISSN
0003-9942
1538-3687 [online]
Volume/pages
69:9(2012), p. 1113-1118
ISI
000308560600002
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 22.11.2012
Last edited 24.06.2017
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