Publication
Title
Assessment of antimicrobial and antiprotozoal activity of the olive oil macerate samples of **Hypericum perforatum** and their LC-DAD-MS analyses
Author
Abstract
Twenty-one samples of traditionally-prepared (home-made) and ready-made (commercial) St. Johns Wort olive oil macerates were profiled for their in vitro antimicrobial and antiprotozoal activity. Their cytotoxic potential was evaluated on MRC-5 fibroblasts. In the antiprotozoal assays, ten of the oils inhibited T. brucei rhodesiense (IC50 15.9 - 64.5 μg/mL), while only one oil exerted antimicrobial activity towards S. aureus (IC50= 88.7 μg/mL). LC-DAD-MS data revealed the presence of pseudohypericin (0.135-3.280 μg/g) and hypericin (0.277-6.634 μg/g) in all the oils, whereas chlorogenic acid (1.063 μg/g) was detected only in one oil sample. Hyperforin was detected in four (0.977-2.399 μg/g) and adhyperforin in six samples (0.005-3.165 μg/g). Hypericin and pseudohypericin were common in the active oils, whereas hyperforin, adhyperforin, and chlorogenic acid were absent in these samples. Our results indicated that if the correct plant material is used, the infused oils from H. perforatum may contain active components.
Language
English
Source (journal)
Food chemistry. - Amsterdam
Publication
Amsterdam : 2013
ISSN
0308-8146
DOI
10.1016/J.FOODCHEM.2012.11.053
Volume/pages
138 :2-3 (2013) , p. 870-875
ISI
000316039500023
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identifier
Creation 28.11.2012
Last edited 04.03.2024
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