Publication
Title
Antiplasmodial and cytotoxic activities of **Striga asiatica** and **Sauropus spatulifolius** extracts, and their isolated constituents
Author
Abstract
A phytochemical investigation of Striga asiatica and the leaves of Sauropus spatulifolius revealed seventeen compounds, three of which were reported for the first time from nature, i.e. two alkaloids N-hydroxyethyl-2-acetylpyrrole, N-(3-carboxypropyl)-2-acetylpyrrole, and 2-(4-hydroxy-2,2,6-trimethylcyclohexyl)acetic acid, for which the name sauropic acid was adopted. Their structures were established spectroscopically and by single-crystal X-ray diffraction analysis. All extracts and isolates were evaluated for antiplasmodial activity against Plasmodium falciparum strain K1 and for cytotoxicity against MRC-5 cells.
Language
English
Source (journal)
Phytochemistry letters
Publication
2013
ISSN
1874-3900
Volume/pages
6:1(2013), p. 53-58
ISI
000314477900012
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 03.12.2012
Last edited 08.07.2017
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