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Title
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Hazelnut allergy : a multi-faced condition with demographic and geographic characteristics
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Author
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Abstract
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| Hazelnut (Corylus avellana) allergy varies from rather mild oral allergy symptoms to potentially life-threatening anaphylaxis and exhibits geographic and age-related variations. Severity of symptoms depends on the sensitisation profile of the patient and can partially be predicted using component-resolved diagnosis. In our region (young) children predominantly exhibit sensitisation to hazelnut storage proteins Cor a 9 and Cor a 11 that is unrelated to birch pollen allergy and is generally associated with a more severe clinical outcome on consumptionon raw and processed hazelnut. In contrast, adults predominantly present with an oral allergy syndrome due to an extensive cross-reactivity between the labile Cor a 1.04 and Bet v 1, the major allergen from birch (Betula verrucosa) pollen. In the absence of a cure, avoidance remains the key measure of effective management, particularly in those patients presenting with a severe form. |
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Language
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English
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Source (journal)
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Acta clinica Belgica. - Leuven, 1946 - 1997
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Publication
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Leuven
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2012
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ISSN
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0001-5512
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DOI
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10.2143/ACB.67.5.2062683
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Volume/pages
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(2012)
, 5 p.
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ISI
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000208851700003
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Full text (Publisher's DOI)
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Full text (publisher's version - intranet only)
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