Publication
Title
Gastric emptying in healthy newborns fed an intact protein formula, a partially and an extensively hydrolysed formula
Author
Abstract
Background & aims: Gastric emptying (GE) is influenced by the type of nutrition. The objective of this study was to compare GE in infants fed an intact protein formula (IPF), a partially hydrolysed formula (PHF), and an extensively hydrolysed formula (EHF). Methods: This was a double-blind, randomized, cross-over study. Following a fasting period of >= 3 h, 20 healthy newborns were fed IPF, PHF, and EHF containing 50 mu l C-13-octanoic acid (OA). Breath samples were taken before feeding and every 15 min for 4 h thereafter. C-13-OA breath test was assessed by isotope-ratio mass spectrometry, and GE half-times (t(1/2)) were determined. Results: Seventeen infants with a mean gestational age of 37 wk (range 28-40 wk) and birth weight of 2698 g (range 720-3690 g) completed the study. At study initiation, the mean age was 31 d (range 6 d-1 3 wk) and the mean weight was 3466 g (range 2100-5700 g). EHF emptied significantly faster than IPF and PHF (medians 46 vs. 55 and 53 min, respectively, Wilcoxon, P < 0.05 for both). There was no significant difference between GE of PHF and IPF (Wilcoxon, P = 0.2). Conclusions: EHF may be better tolerated by infants with GE problems. (c) 2008 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.
Language
English
Source (journal)
Clinical nutrition. - Edinburgh
Source (book)
Digestive Disease Week, 2004, Orlando, FL
Publication
Edinburgh : 2008
ISSN
0261-5614
Volume/pages
27:2(2008), p. 264-268
ISI
000255571900014
Full text (Publishers DOI)
Full text (publishers version - intranet only)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 03.01.2013
Last edited 14.04.2017
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