Publication
Title
Small dense-cored vesicles are depleted of the classical synaptic vesicle membrane proteins synaptobrevin, synaptotagmin and Rab3
Author
Abstract
To verify the association of vesicular docking/fusion proteins to small dense-cored vesicles, we further purified a small dense-cored vesicle population from rat vas deferens and searched for three components of the vesicular docking/fusion machinery known to act on target receptors at the plasma membrane: synaptobrevin (p18), synaptotagmin (p65) and the small GTPase Rab3. Further purification of small dense-cored vesicles actually resulted in a depletion of these proteins, arguing against a direct participation of small dense-cored vesicles in the exocytotic process. This finding points to a functional difference between small dense-cored vesicles and either large dense-cored or small clear synaptic vesicles.
Language
English
Source (journal)
Neuroscience research communications. - Chichester
Publication
Chichester : 2001
ISSN
0893-6609
Volume/pages
28:3(2001), p. 173-179
ISI
000169591300004
Full text (Publisher's DOI)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 03.01.2013
Last edited 08.09.2017
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