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Title
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The course of vasospasm following subarachnoid hemorrhage in rats : a vertebrobasilar angiographic study
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Author
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Abstract
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| The course of vasospasm following subarachnoid haemorrhage in rats was studied using vertebrobasilar angiography. Wistar and Sprague Dawley rats were compared with respect to vasospastic response after bleeding. A more pronounced vasospasm was found in Sprague Dawley rats. In order to avoid a possible toxic effect on the contrast medium, only one angiogram per animal was initially performed. However, a comparison with the results obtained in a separate series of non-challenged animals demonstrated a difficulty due to high variability in basilar artery size in the latter group. Therefore, vasospasm can be more readily shown if multiple angio-grams are used in the same animal so that the vasospasm can be expressed as a percentage of the initial diameter of the basilar artery. It was found that multiple angiograms are well tolerated when non-ionic contrast media are used. |
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Language
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English
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Source (journal)
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Acta neurochirurgica. - Wien, 1950, currens
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Publication
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Wien
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1992
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ISSN
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0001-6268
[print]
0942-0940
[online]
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DOI
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10.1007/BF01400635
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Volume/pages
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117
:1-2
(1992)
, p. 48-52
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ISI
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A1992JJ23700009
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Full text (Publisher's DOI)
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