Publication
Title
Therapeutic potential of nitric oxide donors in the prevention and treatment of atherosclerosis
Author
Abstract
Well-known risk factors for atherosclerosis include hypercholesterolaemia, hypertension, diabetes, and smoking. These conditions are associated with endothelial dysfunction, which itself is associated with reduced endothelial generation of nitric oxide (NO). This is an overview of the implications of NO generation in atherosclerosis and of the potential therapeutic benefit of drugs which donate NO, such as organic nitrates, nicorandil, and sydnonimines, or those which increase the availability of endogenous NO, such as statins, angiotensin-converting enzyme inhibitors, L-arginine, and tetrahydrobiopterin.
Language
English
Source (journal)
European heart journal. - London
Publication
London : 2005
ISSN
0195-668X [Print]
1522-9645 [Online]
Volume/pages
26:19(2005), p. 1945-1955
ISI
000232103200006
Full text (Publisher's DOI)
Full text (open access)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
External links
Web of Science
Record
Identification
Creation 03.01.2013
Last edited 20.11.2017