Title
Unclassified rhabdomyosarcoma in a patient with anti-Hu syndrome Unclassified rhabdomyosarcoma in a patient with anti-Hu syndrome
Author
Publication type
article
Publication
Leuven ,
Subject
Human medicine
Source (journal)
Acta clinica Belgica. - Leuven, 1946 - 1997
Volume/pages
60(2005) :5 , p. 248-251
ISSN
0001-5512
ISI
000236055200005
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Abstract
Anti-Hu syndrome is a paraneoplastic neurological syndrome, most frequently associated with small cell carcinoma of the lung. Subacute sensory neuronopathy is thought to be the most frequent presentation of the anti-Hu syndrome, but it seems that sensory-motor neuropathy is the most common form in the anti-Hu neuropathy. Neurological symptoms often appear before the associated cancer has been identified. Sometimes the tumor is discovered months or even a few years after the appearance of the neurological syndrome. FDG-PET scan seems a better method for finding the tumor in patients with paraneoplastic neurological syndrome and anti-Hu antibodies who had negative test results after an initial workup using radiological methods. In this case report we present a patient with the anti-Hu syndrome associated with an unclassified rhabdornyosarcoma with epitheloid cellular morphology and neuroendocrine differentiation.
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