Title
Electrical stimulation of the anterior limbs of the internal capsules in patients with severe obsessive-compulsive disorder: anecdotal reports Electrical stimulation of the anterior limbs of the internal capsules in patients with severe obsessive-compulsive disorder: anecdotal reports
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
Philadelphia, Pa ,
Subject
Human medicine
Source (journal)
Neurosurgery clinics of North America. - Philadelphia, Pa
Volume/pages
14(2003) :2 , p. 267-274
ISSN
1042-3680
ISI
000182529500009
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
A few unpublished observations from six patients operated on by our group shed light on some effects induced by electric stimulation of the anterior limbs of the internal capsules in patients with severe incapacitating and treatment-resistant obsessive-compulsive disorder. Symptomatic improvement was observed, but after some months, the amplitude required to induce beneficial effects rose to high levels. The use of a programming device given to the patients as one of the strategies to reduce battery consumption helped to illustrate the immediate effects that can be achieved by this kind of electric stimulation. When the battery of one stimulator needed replacement, the symptoms got worse, and the symptoms degraded even further when both stimulators were empty. The reaction from the patients' relatives to the improvement in symptoms has to be taken into account, and psychiatric follow-up remains necessary. Both the beneficial and side effects induced by anterior capsular stimulation are a valuable source for further neurophysiologic and neuroanatomic research.
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