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Title
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Automatic quantification of neurite outgrowth by means of image analysis
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Author
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Abstract
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| A system for quantification of neurite outgrowth in in-vitro experiments is described. The system is developed for routine use in a high-throughput setting and is therefore needs fast, cheap, and robust. It relies on automated digital microscopical imaging of microtiter plates. Image analysis is applied to extract features for characterisation of neurite outgrowth. The system is tested in a dose-response experiment on PC12 cells + Taxol. The performance of the system and its ability to measure changes on neuronal morphology is studied. |
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Language
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English
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Source (journal)
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Progress in biomedical optics and imaging
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PROCESSING XI
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Source (book)
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Conference on 3-Dimensional and Multidimensional Microscopy - Image, Acquisition and Processing XI, JAN 27-29, 2004, San Jose, CA
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Publication
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2004
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ISBN
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0-8194-5232-7
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DOI
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10.1117/12.525634
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Volume/pages
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5
:13
(2004)
, p. 1-7
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ISI
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000223297800001
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Full text (Publisher's DOI)
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