A structural model for the copper(II) site of Cu-Zn superoxide dismutase: preparation, crystal structure and properties of <script type="math/tex">[Cu(Mebta)_{4}(H_{2}O)](CIO_{4})_{2}\cdot0.4</script> EtOH (Mebta=1-methylbenzotriazole)

Skorda, K.; Perlepes, S.P.; Raptopoulou, C.P.; Keuleers, R.; Terzis, A.; Plakatouras, J.C.

doi:10.1023/A:1006988106184

Title

A structural model for the copper(II) site of Cu-Zn superoxide dismutase: preparation, crystal structure and properties of $[Cu(Mebta)_{4}(H_{2}O)](CIO_{4})_{2}\cdot0.4$ EtOH (Mebta=1-methylbenzotriazole)

Author

Skorda, K.

Perlepes, S.P.

Raptopoulou, C.P.

Keuleers, R.

Terzis, A.

Plakatouras, J.C.

Abstract

Reaction of Cu(ClO4)(2). 6H(2)O with 1-methylbenzotriazole (Mebta) in EtOH yields [Cu(Mebta)(4)(H2O)] (ClO4)(2). 0.4EtOH in ca. 75% yield. The structure of this salt has been determined by single-crystal X-ray crystallography. Mebta behaves as a monodentate ligand binding through N(3). The metal coordination geometry is best described as distorted square pyramidal with the H2O ligand occupying the apical site. The complex was also characterized by molar conductivity, room-temperature effective magnetic moment and spectroscopic (i.r., far-i.r., u.v./vis, e.s.r.) studies. The data are discussed in terms of the nature of bonding and known structure. Comparison between the structural and spectroscopic properties of [Cu(Mebta)(4)(H2O)](ClO4)(2). 0.4EtOH and those of the (CuI)-I-I site of Cu-Zn superoxide dismutase shows that the former can be considered as a fairly good model for the latter.

Language

English

Source (journal)

Transition metal chemistry. - Weinheim

Publication

Weinheim : 1999

ISSN

0340-4285

DOI

10.1023/A:1006988106184

Volume/pages

24 :5 (1999) , p. 541-545