Title
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Drug-induced spongiform leucoencephalopathy, a case report with review of the literature
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Author
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Abstract
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A nineteen year-old girl developed rhabdomyolysis and central pyrexia after the ingestion of multiple drugs: amphetamines, benzodiazepines, methadone, ethanol. and cocaine. On admission, the patient was deeply comatose and during the hospitalisation asymmetrical spastic quadriparesis was noted. Brain biopsy was diagnostic of spongiform leucoencephalopathy. A review of the literature concerning drug-induced spongiform encephalopathy revealed a large amount of heroin-induced cases, The role of cocaine, however; is less well described. After prolonged hospitalisation, our patient improved clinically and radiologically and could be transferred to a rehabilitation center. |
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Language
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English
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Source (journal)
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Acta neurologica Belgica. - Bruxelles, 1970, currens
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Publication
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Bruxelles
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Acta Medica Belgica
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1998
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ISSN
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0300-9009
[print]
2240-2993
[online]
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Volume/pages
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98
:1
(1998)
, p. 32-35
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ISI
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000074116600006
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