Title
Controlled auxotonic twitch in papillary muscle : a new computer-based control approach Controlled auxotonic twitch in papillary muscle : a new computer-based control approach
Author
Faculty/Department
Faculty of Pharmaceutical, Biomedical and Veterinary Sciences. Pharmacy
Faculty of Medicine and Health Sciences
Publication type
article
Publication
New York, N.Y. ,
Subject
Human medicine
Computer. Automation
Source (journal)
Computers and biomedical research. - New York, N.Y.
Volume/pages
33(2000) :6 , p. 398-415
ISSN
0010-4809
ISI
000166266500004
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
Based on new advancements in digital technology, we developed a PC- and DSP-based measurement and control system for isolated papillary muscle cxperiments. High flexibility was obtained through a three level control. Length or force was controlled real-time with a sample frequency of 5000 Hz. Muscle length and up to three Segment lengths were measured simultaneously and each of these lengths could he chosen as feedback variable. Individual algorithms were implemented for different twitch types. Batches of twitches were organized in experiment protocols. The system included a new twitch type, namely a controlled auxotonic twitch. In this twitch, the muscle acted against a virtual ideal spring. giving a proportional change in developed force and shortening. The value of the virtual spring constant could he set on-line or defined in the experiment protocol. An increasing virtual spring constant represented a smooth transition from isotonic to isometric conditions. (C) 2000 Academic Press.
E-info
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