Publication
Title
Tumour necrosis factor alpha increases melphalan concentration in tumour tissue after isolated limb perfusion
Author
Abstract
Several possible mechanisms for the synergistic anti-tumour effects between tumour necrosis factor alpha (TNF-alpha) and melphalan after isolated limb perfusion (ILP) have been presented. We found a significant sixfold increase in melphalan tumour tissue concentration after ILP when TNF-alpha was added to the perfusate, which provides a straightforward explanation for the observed synergism between melphalan and TNF-alpha in ILP. (C) 2000 Cancer Research Campaign.
Language
English
Source (journal)
The British journal of cancer. - London
Publication
London : 2000
ISSN
0007-0920
Volume/pages
82:5(2000), p. 1000-1003
ISI
000085696800002
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 03.01.2013
Last edited 07.08.2017
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