Title
Molecular evolution and the incorporation of site-to-site rate variation in distance tree construction methods Molecular evolution and the incorporation of site-to-site rate variation in distance tree construction methods
Author
Faculty/Department
Faculty of Pharmaceutical, Biomedical and Veterinary Sciences . Biomedical Sciences
Publication type
article
Publication
Brussel ,
Subject
Biology
Source (journal)
Belgian journal of zoology. - Brussel
Source (book)
5th Benelux Congress of Zoology, NOV 06-07, 1998, GHENT, BELGIUM
Volume/pages
129(1999) :1 , p. 5-15
ISSN
0777-6276
ISI
000079069100002
Carrier
E
Target language
English (eng)
Affiliation
University of Antwerp
Abstract
The construction of evolutionary trees based on sequence data is not self-evident Apart from the plethora of methods and software tools to choose from if one wants to infer phylogenetic tree topologies, one has also to be cautious about the sequence data themselves. In this paper, we discuss how systematic errors can be introduced by one of the phenomena that often characterize sequence data, i.e. differences in substitution rates among the different sites of the molecule. Regarding painwise distance methods, these systematic errors can often be avoided if an appropriate substitution model is applied to the construction of phylogenetic trees. This is demonstrated for a phylogeny based on animal small subunit ribosomal RNA sequences.
E-info
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000079069100002&DestLinkType=RelatedRecords&DestApp=ALL_WOS&UsrCustomerID=ef845e08c439e550330acc77c7d2d848
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000079069100002&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=ef845e08c439e550330acc77c7d2d848
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000079069100002&DestLinkType=CitingArticles&DestApp=ALL_WOS&UsrCustomerID=ef845e08c439e550330acc77c7d2d848
Handle