Publication
Title
Effect of amphetamine on long-term retention of verbal material
Author
Abstract
A series of five experiments was conducted to investigate the temporal aspects of human memory consolidation of symbolic material through the administration of amphetamine. Subjects had to recall or recognise unrelated words from a previously presented list. The first experiments support the conjecture, based on animal studies, that amphetamine enhances longterm memory performance. Subsequently, enhancement is demonstrated with oral administration before learning, as well as with intramuscular injection after learning. It is shown that improved recall cannot be explained solely by general arousal or attentional processes, but must be due to consolidation. By introducing different test delays we show that consolidation of symbolic material can be modulated by amphetamine during the ist hour after learning. In a final experiment we demonstrate that the memory enhancement applies to to recall as well as to recognition. The implications of the present results are discussed in the context of recent research on LTP processes.
Language
English
Source (journal)
Psychopharmacology. - Berlin
Publication
Berlin : 1995
ISSN
0033-3158
Volume/pages
119:2(1995), p. 155-162
ISI
A1995RB39300005
Full text (Publisher's DOI)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 03.01.2013
Last edited 16.08.2017
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