Publication
Title
Monofluorinated aziridines in asymmetric synthesis of chiral fluorinated prop-2-yn-1-amines
Author
Abstract
Nonracemic C-fluoroaziridines were synthesized for the first time by reaction of fluorocarbene with N-diphenylmethylidene-substituted natural amino acid esters. The products were shown to be used in asymmetric synthesis of chiral fluorinated prop-2-yn-1-amines via one-pot process involving isomerization of 2-fluoroaziridines into alpha-fluoro imines and subsequent reaction with alkynyldifluoroborane generated in situ.
Language
English
Source (journal)
Russian journal of organic chemistry. - New York
Publication
New York : 2010
ISSN
1070-4280
Volume/pages
46:7(2010), p. 976-986
ISI
000280923200004
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
External links
Web of Science
Record
Identification
Creation 28.01.2013
Last edited 24.06.2017