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Synthesis of benzo[f]isoindole-4,9-diones
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| Author |
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| Abstract |
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| A synthesis of benzo[f]isoindole-4,9-diones 1 is presented starting from the reaction of 2,3-bis(bromomethyl)-1,4-dimethoxynaphthalene 15 with primary amines affording 2,3-bis(aminomethyl)-1,4-dimethoxynaphthalenes 14, which could be converted by CAN-mediated oxidation in one step to benzo[f]isoindole-4,9-diones 1. An alternative synthesis of benzo[f]isoindole-4,9-diones 1 starts from 2,3-bis(bromomethyl)1,4-naphthoquinone 9 via 2,3-dihydrobenzo[f]isoindoles 10 which spontaneously oxidize. | | |
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English
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| Source (journal) |
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The journal of organic chemistry. - Washington, D.C. | |
| Publication |
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Washington, D.C. : 2008
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0022-3263
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| Volume/pages |
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73:19(2008), p. 7555-7559
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| ISI |
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000259574700015
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