Publication
Title
A simple route to side-chain fluorinated -lactams from ring-fluorinated aziridines
Author
Abstract
beta-Lactams bearing a Ph2CF substituent at the C(4)-atorn were synthesized from N-alkyl-2-fluoro-3,3-diphenylaziridines. The transformation was realized using SbF3-mediated isomerization of the monofluoroaziridines to fluorinated aldimines, followed by Staudinger reaction with ketenes. It was shown that this reaction sequence can be performed as a one-pot procedure. (c) 2006 Elsevier B.V. All rights reserved.
Language
English
Source (journal)
Journal of fluorine chemistry. - Lausanne
Publication
Lausanne : 2007
ISSN
0022-1139
Volume/pages
128:2(2007), p. 114-119
ISI
000244329900004
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Publication type
Subject
External links
Web of Science
Record
Identification
Creation 28.01.2013
Last edited 02.10.2017