Publication
Title
Novel boronic acid Mannich reactions of ,-dichloro- and ,,-trichloroaldehydes with arylboronic acids
Author
Abstract
A novel variation of the boronic acid Mannich (BAM) reaction is described, in which alpha,alpha-dichloro- and alpha,alpha,omega-trichloroaldehydes, morpholine, and arylboronic acids are used. During this one-pot reaction in refluxing toluene, 1-phenyl-1-morpholinoalkan-2-ones form in moderate yields. The dichloromethylene group is formally converted into a ketone functionality and as such acts as a masked carbonyl group.
Language
English
Source (journal)
Synthesis : journal of synthetic organic chemistry. - Stuttgart, 1969, currens
Publication
Stuttgart : Thieme, 2007
ISSN
0039-7881 [print]
1437-210X [online]
Volume/pages
3(2007), p. 433-441
ISI
000244299300016
Full text (Publisher's DOI)
UAntwerpen
Faculty/Department
Publication type
Subject
External links
Web of Science
Record
Identification
Creation 28.01.2013
Last edited 30.10.2017