Title
Novel boronic acid Mannich reactions of <tex>$\alpha$</tex>,<tex>$\alpha$</tex>-dichloro- and <tex>$\alpha$</tex>,<tex>$\alpha$</tex>,<tex>$\omega$</tex>-trichloroaldehydes with arylboronic acids Novel boronic acid Mannich reactions of <tex>$\alpha$</tex>,<tex>$\alpha$</tex>-dichloro- and <tex>$\alpha$</tex>,<tex>$\alpha$</tex>,<tex>$\omega$</tex>-trichloroaldehydes with arylboronic acids
Author
Faculty/Department
Faculty of Sciences. Chemistry
Publication type
article
Publication
Stuttgart ,
Subject
Chemistry
Source (journal)
Synthesis: journal of synthetic organic chemistry. - Stuttgart
Volume/pages
(2007) :3 , p. 433-441
ISSN
0039-7881
ISI
000244299300016
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Abstract
A novel variation of the boronic acid Mannich (BAM) reaction is described, in which alpha,alpha-dichloro- and alpha,alpha,omega-trichloroaldehydes, morpholine, and arylboronic acids are used. During this one-pot reaction in refluxing toluene, 1-phenyl-1-morpholinoalkan-2-ones form in moderate yields. The dichloromethylene group is formally converted into a ketone functionality and as such acts as a masked carbonyl group.
E-info
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000244299300016&DestLinkType=RelatedRecords&DestApp=ALL_WOS&UsrCustomerID=ef845e08c439e550330acc77c7d2d848
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000244299300016&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=ef845e08c439e550330acc77c7d2d848
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000244299300016&DestLinkType=CitingArticles&DestApp=ALL_WOS&UsrCustomerID=ef845e08c439e550330acc77c7d2d848