Title
Novel synthesis of indolizidines and quinolizidines Novel synthesis of indolizidines and quinolizidines
Author
Faculty/Department
Faculty of Sciences. Chemistry
Publication type
article
Publication
Oxford ,
Subject
Chemistry
Source (journal)
Tetrahedron. - Oxford
Volume/pages
59(2003) :17 , p. 3099-3108
ISSN
0040-4020
ISI
000182418000010
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Abstract
A very short synthesis of indolizidines, quinolizidines and some higher homologues was developed by alkylation of 2-methyl-1-pyrroline or 6-methyl-2,3,4,5-tetrahydropyridine with 1,3- or 1,4-dihaloalkanes, followed by reduction of the intermediate intiniurn salts, resulting in the desired 1-azabicyclo[m.n.0]alkanes in good yields. (C) 2003 Elsevier Science Ltd. All rights reserved.
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