Title
Synthesis of 3-halopyrroles
Author
Faculty/Department
Faculty of Sciences. Chemistry
Publication type
article
Publication
Oxford ,
Subject
Chemistry
Source (journal)
Tetrahedron. - Oxford
Volume/pages
53(1997) :10 , p. 3693-3706
ISSN
0040-4020
ISI
A1997WM13000025
Carrier
E
Target language
English (eng)
Abstract
3-Chloro- and 3-bromo-2-arylpyrroles, which are potential physiologically active compounds in agrochemistry and pharmaceutical sciences, were efficiently prepared from the corresponding 2-aryl-1-pyrrolines by alpha,alpha-dihalogenation with N-halosuccinimides and subsequent base-induced monodehydrohalogenation using sodium methoxide in methanol. (C) 1997 Elsevier Science Ltd.
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