|
Title
|
|
|
|
Probiotics enhance the clearance of human papillomavirus-related cervical lesions : a prospective controlled pilot study
| |
|
Author
|
|
|
|
| |
|
Abstract
|
|
|
|
| Probiotics have been proposed for a number of urogenital infectious conditions. In this study, we examine a possible effect on human papillomavirus (HPV)-related precancerous lesions in cervical cytology. We conducted a prospective controlled pilot study, in which 54 women with an HPV + low-grade squamous intraepithelial lesion diagnosis in their PAP smear were followed for 6 months. The intervention group consumed a daily probiotic drink during the study period; the control group received no treatment, according to common care policy. Outcome measures were the control PAP smear and HPV status after 6 months. Probiotic users had a twice as high chance of clearance of cytological abnormalities (60 vs. 31%, P=0.05). HPV was cleared in 19% of control patients versus 29% of probiotic users (P=0.41). This exploratory pilot study suggests that the probiotic studied promotes the clearance of HPV-related cytological abnormalities. If confirmed, this would represent an entirely new option to manage cervical cancer precursors. European Journal of Cancer Prevention 22:46-51 (C) 2012 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins. European Journal of Cancer Prevention 2013, 22:46-51 |
| |
|
Language
|
|
|
|
English
| |
|
Source (journal)
|
|
|
|
European journal of cancer prevention. - Oxford, 1991, currens
| |
|
Publication
|
|
|
|
Oxford
:
2013
| |
|
ISSN
|
|
|
|
0959-8278
[print]
1473-5709
[online]
| |
|
DOI
|
|
|
|
10.1097/CEJ.0B013E328355ED23
| |
|
Volume/pages
|
|
|
|
22
:1
(2013)
, p. 46-51
| |
|
ISI
|
|
|
|
000311901900007
| |
|
Full text (Publisher's DOI)
|
|
|
|
| |
|