Publication
Title
Synthesis, evaluation and structure-activity relationships of triazine dimers as novel antiviral agents
Author
Abstract
This letter reports the synthesis and structure-activity relationship (SAR) study of a series of triazine dimers as novel antiviral agents. These compounds were obtained through a bivalent ligand approach in which two triazine moieties are covalently connected by suitable linkers. Several compounds showed submicromolar activity against wild-type HIV-1 and moderate activity against single mutant strains. (C) 2012 Elsevier Ltd. All rights reserved.
Language
English
Source (journal)
Bioorganic and medicinal chemistry letters. - Oxford
Publication
Oxford : 2012
ISSN
0960-894X
Volume/pages
22:23(2012), p. 7174-7178
ISI
000310583100037
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Research group
[E?say:metaLocaldata.cgzprojectinf]
Combined highly active anti-retroviral microbicides (CHAARM).
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 04.02.2013
Last edited 06.10.2017
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