Title
Exposure of **Enchytraeus albidus** to Cd and Zn : changes in cellular energy allocation (CEA) and linkage to transcriptional, enzymatic and reproductive effects Exposure of **Enchytraeus albidus** to Cd and Zn : changes in cellular energy allocation (CEA) and linkage to transcriptional, enzymatic and reproductive effects
Author
Faculty/Department
Faculty of Sciences. Biology
Publication type
article
Publication
Oxford ,
Subject
Chemistry
Biology
Source (journal)
Chemosphere. - Oxford, 1972, currens
Volume/pages
90(2013) :3 , p. 1305-1309
ISSN
0045-6535
1879-1298
0045-6535
ISI
000312978700055
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
Cellular energy allocation (CEA) is a measure of the energy status of an organism. The effects of Cd and Zn (reproduction EC50s and EC90s) on the total energy budget of Enchytraeus albidus (Oligochaeta) were assessed through CEA determination, over periods of time from 0 to 8 d. Results showed reduction on the energy reserves for both metals after 2 d exposure. Lipids were the first reserves to be used and carbohydrates were reduced exclusively after Cd exposure. Electron transport system (ETS) activities were enhanced, suggesting increased metabolism and higher energy requirements for metal detoxification. This was supported by previous results at transcription level, where an up-regulation of genes involved in the mitochondrial oxidative phosphorylation was verified. Additionally, the reduction of CEA may be related with the decrease on the reproductive output. These results showed the relevance of integrating various endpoints, which enabled an overview of various processes and to unravel mechanisms of action of chemicals.
E-info
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