Publication
Title
Identification of new members of the (short) neuropeptide F family in locusts and **Caenorhabditis elegans**
Author
Abstract
Both the long and short neuropeptides F (NPF) represent important families of invertebrate neuropeptides that have been implicated in the regulation of reproduction and feeding behavior. In the present study, two short NPFs (SNRSPS(L)/(I)R(L)/(I)RFamide and SpS(L)/(I)R(L)/(I)RFamide) were de novo sequenced by mass spectrometry in two major pest insects, the desert locust Schistocerca gregaria and the African migratory locust Locusta migratoria. They are two of the most widespread peptides in the locust neuroendocrine system. A peptide that was previously reported to accelerate egg development in S. gregaria is shown to represent a truncated form of long NPF. This peptide is most likely derived by a novel processing mechanism involving cleavage at RY. In addition, an NPF peptide from the nematode Caenorhabditis elegans was isolated and sequenced by tandem mass spectrometry.
Language
English
Source (journal)
Annals of the New York Academy of Sciences / New York Academy of Sciences. - New York, N.Y.
Publication
New York, N.Y. : 2009
ISSN
0077-8923
Volume/pages
1163(2009), p. 60-74
ISI
000266493400005
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Publication type
Subject
External links
Web of Science
Record
Identification
Creation 11.03.2013
Last edited 25.06.2017