Title
APRP, the second peptide encoded by the adipokinetic hormone gene(s), is highly conserved in evolution : a role in control of ecdysteroidogenesis?
Author
Faculty/Department
Faculty of Sciences. Biology
Publication type
article
Publication
New York, N.Y. ,
Subject
Human medicine
Engineering sciences. Technology
Source (journal)
Annals of the New York Academy of Sciences / New York Academy of Sciences. - New York, N.Y.
Volume/pages
1163(2009) , p. 376-378
ISSN
0077-8923
0077-8923
ISI
000266493400041
ISBN
978-1-57331-671-2
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Abstract
Since the early days of cloning the first adipokinetic hormone (AKH) gene, researchers recognized that this gene also codes for a joining region and for a second peptide called adipokinetic hormone precursor related peptide (APRP). In species with more than one AKH gene, such as locusts, APRPs can form both homodimers and heterodimers. Database analysis showed that APRPs might belong to the ancient family of growth hormone releasing factor but they still are functionally orphan. We investigated whether some of the APRP forms play a role in control of reproduction or/and growth via stimulation of ecdysteroidogenesis.
E-info
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