Title
PACAP and PDF signaling in the regulation of mammalian and insect circadian rhythms PACAP and PDF signaling in the regulation of mammalian and insect circadian rhythms
Author
Faculty/Department
Faculty of Sciences. Biology
Faculty of Sciences. Chemistry
Faculty of Medicine and Health Sciences
Publication type
article
Publication
Fayetteville, N.Y. ,
Subject
Chemistry
Biology
Pharmacology. Therapy
Source (journal)
Peptides. - Fayetteville, N.Y.
Volume/pages
28(2007) :9 , p. 1775-1783
ISSN
0196-9781
ISI
000250038200023
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Abstract
Endogenous circadian clocks are inherent to all living organisms. They are needed to guarantee successful life since they regulate very important biological processes such as behavior and reproduction. Secretin-like G-protein coupled receptors are very important factors in the signal transduction pathways of circadian clocks. In this review, we will focus on the role of two secretin-like signaling pathways that play an important role in the regulation of the mammalian and the insect clock, respectively: the pituitary adenylate cyclase-activating polypeptide (PACAP) and pigment dispersing factor (PDF) signaling pathways. Both pathways are most likely related although their function in the biological clock differs. (c) 2007 Elsevier Inc. All rights reserved.
E-info
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