Publication
Title
Investigation on the genotoxicity of extracts from **Cleome amblyocarpa** Barr. and Murb, an important Tunisian medicinal plant
Author
Abstract
We conducted an investigation of the in vitro toxic and genotoxic properties of Cleome amblyocarpa Barr. and Murb, which is an important medicinal plant in Tunisia where it is widely used against colic and diabetes. In this study we investigated methanol extracts of the whole plant with the neutral red uptake test for assessing its in vitro toxicity and the alkaline comet assay for genotoxicity. It appeared that the extract was not genotoxic in subtoxic concentrations. However, the neutral red uptake test revealed that it was highly toxic and therefore some caution, especially regarding dosage and frequency of use, is warranted.
Language
English
Source (journal)
South African journal of botany. - Capetown
Publication
Capetown : 2013
ISSN
0254-6299
Volume/pages
84(2013), p. 102-103
ISI
000314261600014
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 28.03.2013
Last edited 04.05.2017
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