Title
Delayed gastric emptying in anorexic adolescents measured with the <tex>$^{13}C$</tex> octanoic acid breath test Delayed gastric emptying in anorexic adolescents measured with the <tex>$^{13}C$</tex> octanoic acid breath test
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
: ,
Subject
Human medicine
Source (journal)
Food and nutrition sciences. - Place of publication unknown
Volume/pages
3(2012) :8 , p. 1043-1047
ISSN
2157-944X
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
Many gastrointestinal complaints and motility disorders are described in patients suffering from different eating disorders. These have a negative impact on refeeding. This report evaluatedon admission-gastric emptying of a standardized solid meal with 13C octanoic acid breath test in anorexic adolescents. The results were compared with age and gender matched controls. Gastric emptying data were related to a subjective symptom score. 21 Anorexic girls and 3 boys (mean age: 15.6 y ± 1.3 y), body mass index (mean 15.6 kg/m2 ± 1.6 kg/m2), weight loss (mean: 22.2% ± 10.7%) were studied. T½ of the gastric emptying time exceeded the P95 in 14/24 (58%) patients, classified as having delayed gastric emptying (DGE). One patient (4%) had a T½ exceeding P75 and was classified as slow (SGE), whereas 9/24 (38%) patients had normal gastric emptying (NGE). In comparison to NGE, subjects with DGE had significantly higher symptom scores (p = 0.01) and more weight loss. The DGE and SGE patients lost 25.29% and 21.38% of weight respectively, whereas a weight loss of 17.64% was found in anorexics with NGE. In conclusion, gastric emptying is delayed in patients with anorexia. This is associated with more significant gastrointestinal symptoms and higher weight loss.
Full text (open access)
https://repository.uantwerpen.be/docman/irua/383509/3a54a49f.pdf
Handle