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Title
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Delayed gastric emptying in anorexic adolescents measured with the octanoic acid breath test
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Author
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Abstract
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| Many gastrointestinal complaints and motility disorders are described in patients suffering from different eating disorders. These have a negative impact on refeeding. This report evaluatedon admission-gastric emptying of a standardized solid meal with 13C octanoic acid breath test in anorexic adolescents. The results were compared with age and gender matched controls. Gastric emptying data were related to a subjective symptom score. 21 Anorexic girls and 3 boys (mean age: 15.6 y ± 1.3 y), body mass index (mean 15.6 kg/m2 ± 1.6 kg/m2), weight loss (mean: 22.2% ± 10.7%) were studied. T½ of the gastric emptying time exceeded the P95 in 14/24 (58%) patients, classified as having delayed gastric emptying (DGE). One patient (4%) had a T½ exceeding P75 and was classified as slow (SGE), whereas 9/24 (38%) patients had normal gastric emptying (NGE). In comparison to NGE, subjects with DGE had significantly higher symptom scores (p = 0.01) and more weight loss. The DGE and SGE patients lost 25.29% and 21.38% of weight respectively, whereas a weight loss of 17.64% was found in anorexics with NGE. In conclusion, gastric emptying is delayed in patients with anorexia. This is associated with more significant gastrointestinal symptoms and higher weight loss. |
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Language
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English
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Source (journal)
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Food and nutrition sciences. - Place of publication unknown
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Publication
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Place of publication unknown
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publisher unknown
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2012
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ISSN
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2157-944X
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DOI
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10.4236/FNS.2012.38138
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Volume/pages
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3
:8
(2012)
, p. 1043-1047
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Full text (Publisher's DOI)
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Full text (open access)
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