Unclassifiable B-cell lymphoma occurring after necrotizing pneumoniaUnclassifiable B-cell lymphoma occurring after necrotizing pneumonia
Faculty of Medicine and Health Sciences
University Hospital Antwerp
Antwerp Surgical Training, Anatomy and Research Centre (ASTARC)
European journal of cardiothoracic surgery. - Berlin
43(2013):3, p. E89-E91
University of Antwerp
We report a case of CD20+ grey zone lymphoma (GZL) with Reed Sternberg cells as an unexpected pathological diagnosis of a destroyed right lower lobe after necrotizing pneumonia. These GZLs show overlapping features of classical Hodgkin's lymphoma and diffuse large B-cell lymphoma. GZLs are a rare specific entity of lymphomas, and the aetiology is unknown. The diagnosis is confirmed by pathological, immunohistochemical and molecular analyses. The optimal treatment is unknown. The prognosis of these patients is poor.