Publication
Title
Infliximab induces remission in cryptogenic multifocal ulcerous stenosing enteritis : first case
Author
Abstract
We present the case of a 29-year-old patient with a history of abdominal pain and vomiting. Based on wireless video capsule findings he was previously diagnosed with ileal Crohn's disease at a different institution, although the clinical and radiological picture was not typical and the response to corticosteroids was poor. We performed a single-balloon enteroscopy showing a short, ulcerous stenosis 50 cm proximal from Bauhin's valve. The endoscopic and clinical histopathological findings were compatible with cryptogenic multifocal ulcerous stenosing enteritis (CMUSE). High dose corticosteroids were again started, without effect. The monoclonal tumor necrosis factor-alpha (TNF-alpha) antibody infliximab was added to the medical therapy. After induction therapy, both clinical and endoscopic amelioration was obtained. Larger case studies are needed to confirm the efficacy of TNF-alpha inhibition in steroid refractory CMUSE. (c) 2013 Baishideng. All rights reserved.
Language
English
Source (journal)
World journal of gastroenterology. - Place of publication unknown
Publication
Place of publication unknown : 2013
ISSN
1007-9327
Volume/pages
19:10(2013), p. 1661-1664
ISI
000316060500022
Full text (Publisher's DOI)
Full text (open access)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 05.06.2013
Last edited 24.09.2017
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