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Title
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Controlling false discovery rates in factorial experiments with between-subjects and within-subjects tests
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Author
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Abstract
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| Background: The False Discovery Rate (FDR) controls the expected number of false positives among the positive test results. It is not straightforward how to conduct a FDR controlling procedure in experiments with a factorial structure, while at the same time there are between-subjects and within-subjects factors. This is because there are P-values for different tests in one and the same response along with P-values for the same test and different responses. Findings: We propose a procedure resulting in a single P-value per response, calculated over the tests of all the factorial effects. FDR control can then be based on the set of single P-values. Conclusions: The proposed procedure is very easy to apply and is recommended for all designs with factors applied at different levels of the randomization, such as cross-over designs with added between-subjects factors. |
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Language
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English
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Source (journal)
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BMC research notes
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Publication
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2013
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ISSN
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1756-0500
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Volume/pages
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6
(2013)
, p. 204-208
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Full text (open access)
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