Title
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Clinical manifestations and case management of ebola haemorrhagic fever caused by a newly identified virus strain, Bundibugyo, Uganda, 2007-2008
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Author
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Abstract
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A confirmed Ebola haemorrhagic fever (EHF) outbreak in Bundibugyo, Uganda, November 2007-February 2008, was caused by a putative new species (Bundibugyo ebolavirus). It included 93 putative cases, 56 laboratory-confirmed cases, and 37 deaths (CFR = 25%). Study objectives are to describe clinical manifestations and case management for 26 hospitalised laboratory-confirmed EHF patients. Clinical findings are congruous with previously reported EHF infections. The most frequently experienced symptoms were non-bloody diarrhoea (81%), severe headache (81%), and asthenia (77%). Seven patients reported or were observed with haemorrhagic symptoms, six of whom died. Ebola care remains difficult due to the resource-poor setting of outbreaks and the infection-control procedures required. However, quality data collection is essential to evaluate case definitions and therapeutic interventions, and needs improvement in future epidemics. Organizations usually involved in EHF case management have a particular responsibility in this respect. |
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Language
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English
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Source (journal)
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PLoS ONE
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Publication
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2012
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ISSN
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1932-6203
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DOI
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10.1371/JOURNAL.PONE.0052986
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Volume/pages
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7
:12
(2012)
, p. 1-12
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Article Reference
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e52986
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ISI
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000313051500095
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Medium
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E-only publicatie
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Full text (Publisher's DOI)
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Full text (open access)
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