Title
Bench-to-bedside review : rapid molecular diagnostics for bloodstream infection - a new frontier? Bench-to-bedside review : rapid molecular diagnostics for bloodstream infection - a new frontier?
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
London ,
Subject
Human medicine
Source (journal)
Critical care. - London
Volume/pages
16(2012) :3 , p. 1-12
ISSN
1364-8535
1364-8535
Article Reference
222
Carrier
E-only publicatie
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
Among critically ill patients, the diagnosis of bloodstream infection poses a major challenge. Current standard bacterial identification based on blood culture platforms is intrinsically time-consuming and slow. The continuous evolvement of molecular techniques has the potential of providing a faster, more sensitive and direct identification of causative pathogens without prior need for cultivation. This may ultimately impact clinical decision-making and antimicrobial treatment. This review summarises the currently available technologies, their strengths and limitations and the obstacles that have to be overcome in order to develop a satisfactory bedside point-of-care diagnostic tool for detection of bloodstream infection.
Full text (open access)
https://repository.uantwerpen.be/docman/irua/9a8d45/5079.pdf
E-info
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