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Title
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Bench-to-bedside review : rapid molecular diagnostics for bloodstream infection - a new frontier?
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Author
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Abstract
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| Among critically ill patients, the diagnosis of bloodstream infection poses a major challenge. Current standard bacterial identification based on blood culture platforms is intrinsically time-consuming and slow. The continuous evolvement of molecular techniques has the potential of providing a faster, more sensitive and direct identification of causative pathogens without prior need for cultivation. This may ultimately impact clinical decision-making and antimicrobial treatment. This review summarises the currently available technologies, their strengths and limitations and the obstacles that have to be overcome in order to develop a satisfactory bedside point-of-care diagnostic tool for detection of bloodstream infection. |
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Language
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English
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Source (journal)
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Critical care. - London
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Publication
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London
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2012
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ISSN
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1364-8535
1466-609X
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DOI
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10.1186/CC11202
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Volume/pages
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16
:3
(2012)
, p. 1-12
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Article Reference
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222
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ISI
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000313197500057
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Medium
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E-only publicatie
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Full text (Publisher's DOI)
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Full text (open access)
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