Title
Current information on sacral neuromodulation and botulinum toxin treatment for refractory idiopathic overactive bladder syndrome : a review Current information on sacral neuromodulation and botulinum toxin treatment for refractory idiopathic overactive bladder syndrome : a review
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
Basel ,
Subject
Human medicine
Source (journal)
Urologia internationalis. - Basel
Volume/pages
84(2010) :3 , p. 245-253
ISSN
0042-1138
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Abstract
The overactive bladder syndrome (OAB) negatively affects the daily life of many people. Conservative treatments, such as antimuscarinics, do not always lead to sufficient improvement of the complaints and/or are often associated with considerable side effects resulting in treatment failure. In the case of failure or intolerable side effects, sacral neuromodulation (SNM) and botulinum toxin are minimally invasive and reversible alternatives. Currently, of these alternatives only SNM with InterStimTM therapy has FDA approval for use in OAB patients. This review attempts to provide an update on the current position of SNM and botulinum toxin in the second-line management of adults with idiopathic OAB, based on the available clinical evidence concerning the efficacy and safety.
E-info
https://repository.uantwerpen.be/docman/iruaauth/036050/d6f719bab13.pdf