Title
Cardiovascular autophagy : concepts, controversies, and perspectives Cardiovascular autophagy : concepts, controversies, and perspectives
Author
Faculty/Department
Faculty of Pharmaceutical, Biomedical and Veterinary Sciences. Pharmacy
Publication type
article
Publication
,
Subject
Biology
Pharmacology. Therapy
Human medicine
Source (journal)
Autophagy. - Place of publication unknown
Volume/pages
9(2013) :10 , p. 1455-1466
ISSN
1554-8627
1554-8635
ISI
000327579000002
Carrier
E
Target language
French (fre)
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
Despite recent scientific and technological advances, cardiovascular disease remains the leading cause of morbidity and mortality worldwide. Autophagy, an evolutionarily ancient response to cellular stress, has been implicated in the pathogenesis of a wide range of heart pathologies. However, the precise role of autophagy in these contexts remains obscure owing to its multifarious actions. Here, we review recently derived insights regarding the role of autophagy in multiple manifestations of cardiac plasticity and disease.
E-info
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