Publication
Title
Therapeutic potential of neuregulin-1 in cardiovascular disease
Author
Abstract
Neuregulin-1 (NRG-1)/ErbB signaling has an indispensable role in cardiac development and in the maintenance of the structural and functional integrity of the human adult heart in health and disease. Several animal studies have now demonstrated the therapeutic effects of NRG-1 during acute cardiac injury and during chronic heart failure, with improvements in cardiac performance and animal survival. Phase I and II clinical trials for chronic heart failure in humans are now in progress.
Language
English
Source (journal)
Drug discovery today. - London
Publication
Oxford : Elsevier sci ltd, 2013
ISSN
1359-6446
Volume/pages
18:17-18(2013), p. 836-842
ISI
000324719500005
Full text (Publishers DOI)
Full text (publishers version - intranet only)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 08.11.2013
Last edited 28.04.2017
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