Publication
Title
Conformational analysis, solvent-accessible surface and geometric extent of inhibitors and substrates
Author
Abstract
Peptide ligands are known to often bind in an extended conformation to maximize the contact surface with the receptor. The complementarity of shape and surface is a very important factor contributing to the stability of a ligand receptor complex. In this communication we try to answer the following questions: What is the influence of conformation on the surface area? Do ligands maximize their contact surface with the receptor to increase stability of the complex?
Language
English
Source (journal)
Collection of Czechoslovak chemical communications. - Praha
Publication
Praha : 2006
ISSN
0010-0765
Volume/pages
71:6(2006), p. 842-858
ISI
000238419500008
Full text (Publishers DOI)
UAntwerpen
Faculty/Department
Publication type
Subject
External links
Web of Science
Record
Identification
Creation 11.12.2013
Last edited 21.04.2017