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Title
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Discovery of pyrimidyl-5-hydroxamic acids as new potent histone deacetylase inhibitors
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Author
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Abstract
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| A series of pyrimidyl-5-hydroxamic acids was prepared for evaluation as inhibitors of histone deacetylase (HDAC). Amino-2-pyrimidinyl can be used as a linker to provide HDAC inhibitors of good enzymatic potency. (c) 2005 Elsevier SAS. All rights reserved. |
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Language
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English
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Source (journal)
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European journal of medicinal chemistry. - Paris, 1974, currens
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Publication
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Paris
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2005
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ISSN
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0223-5234
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DOI
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10.1016/J.EJMECH.2005.01.008
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Volume/pages
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40
:6
(2005)
, p. 597-606
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ISI
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000229895000009
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Full text (Publisher's DOI)
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Full text (publisher's version - intranet only)
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