Title
Properties of oligonucleotides with six membered carbohydrate mimics and a 1,4-relationship between the base moiety and the hydroxymethyl group
Author
Faculty/Department
Faculty of Pharmaceutical, Biomedical and Veterinary Sciences. Pharmacy
Publication type
article
Publication
New York, N.Y. ,
Subject
Chemistry
Biology
Source (journal)
Nucleosides, nucleotides & nucleic acids. - New York, N.Y.
Volume/pages
18(1999) :6-7 , p. 1371-1376
ISSN
1525-7770
ISI
000081805900069
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Abstract
The properties of oligonucleotides with a six-membered carbohydrate mimic in the backbone structure and a 1,4-relationship between the base moiety and the hydroxymethyl group are summarized. The different six-membered rings that were studied are: 1,5-anhydro-2,3-dideoxy-D-arabino-hexitol, 1,5-anhydro-2-deoxy-D-mannitol, 1,5-anhydro-2-deoxy-D-altritol and 3-hydroxy-4-hydroxymethyl-cyclohexane.
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