Publication
Title
Hexitol nucleic acids (HNA): Synthesis and properties
Author
Abstract
While improved alkylation procedures have been worked out for the coupling of purine bases to the anhydrohexitol ring using sulphonate activating groups on the anhydrohexitol ring, the Mitsunobu reaction seems to be the method of choice for synthesis of the pyrimidine analogues. In a mixed sequence context, the anhydrohexitol oligonucleotides still display strong and very selective basepairing properties, with a strong preference for RNA as the complement.
Language
English
Source (journal)
Nucleosides and nucleotides. - New York, N.Y.
Publication
New York, N.Y. : 1997
ISSN
0732-8311
Volume/pages
16:7-9(1997), p. 973-976
ISI
A1997YF53000016
Full text (Publishers DOI)
UAntwerpen
Faculty/Department
Publication type
Subject
External links
Web of Science
Record
Identification
Creation 11.12.2013
Last edited 20.04.2017