Publication
Title
Hexopyranosyl-like oligonucleotides
Author
Abstract
Oligonucleotides containing monomers 1-(2,3-dideoxy-beta-D-erythro-hexopyranosyl)thymine; 1-(2,4-dideoxy-beta-D-erythro-hexopyranosyl)thymine; 1-(3,4-dideoxy-beta-D-erythro-hexo-pyranosyl)-thymine; 1-(2,3-dideoxy-alpha-D-erythro-hexopyranosyl)thymine; 1-[2,3-dideoxy-3-C-(hydroxymethyl)-alpha-L-threo-pentopyranosyl]-thymine; and 1,5-anhydro-2,3 -dideoxy-2(thymin-1-yl)-D-arabinohexitol were modeled and synthesized. Only oligonucleotides constructed of 1,5-anhydrohexitol nucleosides are able to hybridize with natural DNA.
Language
English
Source (journal)
ACS symposium series / American Chemical Society. - Milton keynes
Publication
Milton keynes : 1994
ISSN
0097-6156
Volume/pages
580(1994), p. 80-99
ISI
A1994BB96P00006
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
External links
Web of Science
Record
Identification
Creation 11.12.2013
Last edited 18.09.2017
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