Publication
Title
Structure of 1-(2-deoxy--d-ribopyranosyl)-5-iodouracil
Author
Abstract
1-(2-Deoxy-beta-D-ribopyranosyl)-5-iodouracil, C9H11IN2O5, M(r) = 354.10, monoclinic, P2(1), a = 5.458 (3), b = 8.237 (4), c = 12.812 (6) angstrom, beta = 98.42 (4)-degrees, V = 569.8 (5) angstrom3, Z = 2, D(m) = 2.05, D(x) = 2.063 Mg m-3, lambda-(Mo K-alpha) = 0.71069 angstrom, mu = 2.789 mm-1, F(000) = 344, T = 293 K, final R = 0.039 for 1701 unique observed [F greater-than-or-equal-to 4-sigma(F)] reflections. The sugar ring adopts a slightly flattened chair conformation. The heterocyclic base is placed in an - ap (antiperiplanar) orientation [chi = 196.4 (3)-degrees] with respect to the sugar moiety. Of the three sugar ring substituents, only O(33') is in an axial position. The packing of the crystal is determined by three intermolecular hydrogen bonds, involving O(33'), O(2) and O(44'). The conformational parameters are in accordance with the IUPAC-IUB Joint Commission on Biochemical Nomenclature [Pure Appl. Chem. (1983), 55, 1273-1280] guidelines.
Language
English
Source (journal)
Acta crystallographica: section C: crystal structure communications. - Copenhagen
Publication
Copenhagen : 1991
ISSN
0108-2701
Volume/pages
47:4(1991), p. 835-837
ISI
A1991FJ77300049
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Publication type
Subject
External links
Web of Science
Record
Identification
Creation 11.12.2013
Last edited 25.06.2017