Title
Glycan structure of a high-mannose glycoprotein from Raman optical activity Glycan structure of a high-mannose glycoprotein from Raman optical activity
Author
Faculty/Department
Faculty of Sciences. Chemistry
Publication type
article
Publication
Weinheim ,
Subject
Chemistry
Source (journal)
Angewandte Chemie: international edition in English. - Weinheim
Volume/pages
50(2011) :23 , p. 5349-5351
ISSN
1433-7851
0570-0833
ISI
000291953200021
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Abstract
A revealing signature: The glycan structure of intact yeast external invertase, a high-mannose glycoprotein used as biocatalyst, was investigated by using Raman optical activity (ROA) spectroscopy. The conformational preferences present in mannose-containing di- and trisaccharides were found to be preserved in the glycan chains, with secondary polpeptide backbone structure suppressed.
E-info
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