Title
Application of 3-bromo-3-ethylazetidines and 3-ethylideneazetidines for the synthesis of functionalized azetidines
Author
Faculty/Department
Faculty of Sciences. Chemistry
Publication type
article
Publication
Stuttgart ,
Subject
Chemistry
Source (journal)
Synlett: accounts and rapid communications in synthetic organic chemistry. - Stuttgart
Volume/pages
25(2014) :1 , p. 75-80
ISSN
0936-5214
ISI
000328606500009
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Abstract
The synthetic utility of 3-bromo-3-ethylazetidines has been demonstrated by the straightforward preparation of 3-alkoxy-, 3-aryloxy-, 3-acetoxy-, 3-hydroxy-, 3-cyano-, 3-carbamoyl- and 3-amino-3-ethylazetidines. In addition, 3-bromo-3-ethylazetidines have been successfully deployed as precursors for a convenient synthesis of 3-ethylideneazetidines, which served as starting materials for the preparation of novel functionalized azetidines and spirocyclic azetidine building blocks.
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